What is Jardiance used for?

Key Tips
Jardiance is an sodium-glucose cotransporter-2 (SGLT-2) inhibitor that is used as a supplement to exercise and diet to manage the blood sugar (sugar) in people suffering from Type 2 Diabetes. It reduces blood sugar levels by blocking kidney proteins to boost the excretion of glucose through urine.

Jardiance reduces the risk of dying from heart disease (like a heart attack or stroke) for adults with heart disease. It also reduces the chance of hospitalization and death as a result of the heart’s failure (when your heart has weakens and unable to provide enough blood flow to the other organs parts of the body) for patients suffering from heart failure.

As time passes, high blood sugar levels could cause plaque to build within your blood vessels, increasing the risk of developing heart disease.

What is the process behind Jardiance function?

Jardiance (empagliflozin) is classified as an SGLT-2 (sodium-glucose cotransporter-2) inhibitor. The SGLT-2 proteins reside within the tubules of renal blood of kidneys. They are responsible for absorption of glucose back into the blood. Jardiance hinders the actions on the proteins SGLT-2. In the end, more glucose is excreted from the urine.

For information on the Jardiance patient assistance program click here.

SGLT-2 inhibitors have been proven to be effective in decreasing hemoglobin A1C levels as well as improving weight loss and decreasing blood pressure.

Jardiance is a good addition to other medications for type 2 diabetes, such as pioglitazone, metformin, sulfonylure and insulin as well with other heart-related medications such as beta blockers, statins, ACE inhibitors, and diuretics.

If used on their own, SGLT-2 inhibitors have the lowest risk of developing Hypoglycemia (low glucose levels). However, your physician may require lowering the dose of Jardiance when you are taking it along with other medications which can also result in low blood sugarlevels, such as insulin or Sulfonylureas.

Other FDA approved drugs in the SGLT-2 inhibitor class are:

canagliflozin (Invokana)
dapagliflozin (Farxiga)
ertugliflozin (Steglatro)

They are available as single-ingredient products , or when combined with other diabetes medications.

What can Jardiance assist me with the type 2 Diabetes I suffer from?

When you suffer from type 2 diabetes, the body doesn’t produce enough insulin. The insulin that you make is not as effective and you could produce excessive amounts of sugar (sugar). As this happens, glucose accumulates in your blood , which can cause serious health issues that affect the kidney, heart blood vessels, nerves and eyes. Exercise, diet, and the use of specific medications can reduce the blood sugar levels and reduce the risk from developing type 2 diabetes.

A lot of patients who are identified with diabetes type II begin with an oral medication referred to as metformin. It’s part of the class of drugs known as the biguanides. It improves the ability of cells to utilize glucose (blood sugar) by improving the way your insulin functions and reduces the production of glucose in your liver and its absorption.

Some patients are unable to achieve their blood sugar goals by taking metformin on its own and require additional medications.

Jardiance is a supplement to metformin and other medications to help you achieve your A1C target. A1C is a blood test that displays the average quantity of sugar (glucose) in your blood over the last two to three months, which will let you know how your blood sugar levels are being managed over time.

Who is not a good candidate for Jardiance?

Jardiance is not recommended for people suffering from Type 1 diabetics or those suffering from diabetes ketoacidosis (increased ketones in urine or blood). In patients suffering from type 1 diabetes can increase the risk of diabetic ketoacidosis among these patients.
It is not recommended to use Jardiance in the event that you’ve had a history of an allergic reaction that is severe to Jardiance or any of its components.
It is also advised not to use this medication if you suffer from serious renal (renal) disease or end-stage renal disease or you are on dialysis. Your doctor will test your kidney function prior to you start the treatment process with Jardiance. Jardiance might not be effective in the case of severe kidney issues.

What can I do to take Jardiance?

Take Jardiance every day according to what your doctor has instructed you to do. It is available in 10 – or 25-milligram tablet that you take.

The dosage recommended for Jardiance of 10 mg once every day in the morning whether or not food is consumed. If you’re able to tolerate Jardiance dosage, it can increase to 25 mg if you require it.

Your doctor will test the function of your kidneys with an examination of your blood before you begin treatment. If you are suffering from a specific degree of kidney disease, you might not be able to take advantage of Jardiance.

Do not consume Jardiance in case you are allergic to one of the ingredients.

Jardiance is not suitable for use by anyone less than 18 years old.

Significant side effects associated with Jardiance

Jardiance is generally well-tolerated. But, like any drug, there are significant side effects that you must discuss and review the effects with your physician.

The most serious side effects associated with Jardiance could be:

The condition is known as ketoacidosis (increased ketones in your urine or blood)
Sudden kidney injury
Urinary tract infections
The condition of dehydration (the loss of body fluids and salt)
Blood sugar levels are low (hypoglycemia)
Necrotizing fasciitis (a extremely rare, but severe tissue infection of the skin that may occur in the genitals and around the anus)
Allergy reactions
The increase in cholesterol

The most frequent adverse reactions (5 percent or more) that can occur in Jardiance are:

Urinary tract infections
Infections caused by yeast